| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DeoR | GlpD_1 | BW34_02437 | BW34_02436 | Putative DeoR-family transcriptional regulator. | Glycerol-3-phosphate dehydrogenase. | 0.663 |
| DeoR | RibE | BW34_02437 | BW34_02439 | Putative DeoR-family transcriptional regulator. | Riboflavin synthase, alpha subunit. | 0.412 |
| DeoR | deoC | BW34_02437 | BW34_01916 | Putative DeoR-family transcriptional regulator. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.501 |
| DeoR | glpK | BW34_02437 | BW34_02435 | Putative DeoR-family transcriptional regulator. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.577 |
| DeoR | ribA | BW34_02437 | BW34_02440 | Putative DeoR-family transcriptional regulator. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.545 |
| DeoR | ribD | BW34_02437 | BW34_02438 | Putative DeoR-family transcriptional regulator. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.412 |
| DeoR | ribH | BW34_02437 | BW34_02441 | Putative DeoR-family transcriptional regulator. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.426 |
| GlpD_1 | DeoR | BW34_02436 | BW34_02437 | Glycerol-3-phosphate dehydrogenase. | Putative DeoR-family transcriptional regulator. | 0.663 |
| GlpD_1 | glpK | BW34_02436 | BW34_02435 | Glycerol-3-phosphate dehydrogenase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.978 |
| RibE | DeoR | BW34_02439 | BW34_02437 | Riboflavin synthase, alpha subunit. | Putative DeoR-family transcriptional regulator. | 0.412 |
| RibE | ribA | BW34_02439 | BW34_02440 | Riboflavin synthase, alpha subunit. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
| RibE | ribD | BW34_02439 | BW34_02438 | Riboflavin synthase, alpha subunit. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| RibE | ribH | BW34_02439 | BW34_02441 | Riboflavin synthase, alpha subunit. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| deoC | DeoR | BW34_01916 | BW34_02437 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Putative DeoR-family transcriptional regulator. | 0.501 |
| glpK | DeoR | BW34_02435 | BW34_02437 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Putative DeoR-family transcriptional regulator. | 0.577 |
| glpK | GlpD_1 | BW34_02435 | BW34_02436 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol-3-phosphate dehydrogenase. | 0.978 |
| ribA | DeoR | BW34_02440 | BW34_02437 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | Putative DeoR-family transcriptional regulator. | 0.545 |
| ribA | RibE | BW34_02440 | BW34_02439 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | Riboflavin synthase, alpha subunit. | 0.999 |
| ribA | ribD | BW34_02440 | BW34_02438 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribA | ribH | BW34_02440 | BW34_02441 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |