node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KJL48219.1 | KJL49183.1 | RS84_01851 | RS84_00295 | Von Willebrand factor type A domain protein. | Putative S-adenosylmethionine-dependent methyltransferase. | 0.634 |
KJL49183.1 | KJL48219.1 | RS84_00295 | RS84_01851 | Putative S-adenosylmethionine-dependent methyltransferase. | Von Willebrand factor type A domain protein. | 0.634 |
KJL49183.1 | gcvP | RS84_00295 | RS84_03585 | Putative S-adenosylmethionine-dependent methyltransferase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.759 |
KJL49183.1 | glyA1 | RS84_00295 | RS84_02457 | Putative S-adenosylmethionine-dependent methyltransferase. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.643 |
KJL49183.1 | metG | RS84_00295 | RS84_00297 | Putative S-adenosylmethionine-dependent methyltransferase. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.596 |
KJL49183.1 | pcpB_1 | RS84_00295 | RS84_02482 | Putative S-adenosylmethionine-dependent methyltransferase. | Pentachlorophenol 4-monooxygenase. | 0.568 |
KJL49183.1 | pmt | RS84_00295 | RS84_00293 | Putative S-adenosylmethionine-dependent methyltransferase. | Putative dolichyl-phosphate-mannose--protein mannosyltransferase. | 0.564 |
KJL49183.1 | rsmI | RS84_00295 | RS84_00294 | Putative S-adenosylmethionine-dependent methyltransferase. | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.803 |
KJL49183.1 | ubiB | RS84_00295 | RS84_01158 | Putative S-adenosylmethionine-dependent methyltransferase. | Putative protein kinase UbiB. | 0.585 |
KJL49183.1 | ycfH | RS84_00295 | RS84_00298 | Putative S-adenosylmethionine-dependent methyltransferase. | Putative deoxyribonuclease YcfH. | 0.567 |
KJL49183.1 | yedY | RS84_00295 | RS84_00296 | Putative S-adenosylmethionine-dependent methyltransferase. | Sulfoxide reductase catalytic subunit YedY precursor. | 0.745 |
gcvP | KJL49183.1 | RS84_03585 | RS84_00295 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative S-adenosylmethionine-dependent methyltransferase. | 0.759 |
gcvP | glyA1 | RS84_03585 | RS84_02457 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
glyA1 | KJL49183.1 | RS84_02457 | RS84_00295 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative S-adenosylmethionine-dependent methyltransferase. | 0.643 |
glyA1 | gcvP | RS84_02457 | RS84_03585 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.998 |
glyA1 | metG | RS84_02457 | RS84_00297 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.409 |
metG | KJL49183.1 | RS84_00297 | RS84_00295 | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative S-adenosylmethionine-dependent methyltransferase. | 0.596 |
metG | glyA1 | RS84_00297 | RS84_02457 | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.409 |
metG | pmt | RS84_00297 | RS84_00293 | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative dolichyl-phosphate-mannose--protein mannosyltransferase. | 0.459 |
metG | rsmI | RS84_00297 | RS84_00294 | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.726 |