STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nei1_2Endonuclease 8 1; Belongs to the FPG family. (332 aa)    
Predicted Functional Partners:
nei1_1
Endonuclease 8 1.
  
  
 
0.907
fpg1
Formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
0.854
rpiB
Ribose-5-phosphate isomerase B.
       0.839
polA_2
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.806
paiB_2
Protease synthase and sporulation protein PAI 2.
       0.790
nfdA_5
N-substituted formamide deformylase precursor.
       0.780
fpg2_1
Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family.
  
  
 
0.741
fpg2_2
Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family.
  
  
 
0.739
hemH_2
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
     0.702
deaD_1
ATP-dependent RNA helicase DeaD.
  
  
 0.566
Your Current Organism:
Microbacterium hydrocarbonoxydans
NCBI taxonomy Id: 273678
Other names: DSM 16089, JCM 14340, M. hydrocarbonoxydans, Microbacterium hydrocarbonoxydans Schippers et al. 2005, NBRC 103074, NCIMB 14002, strain BNP48
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