node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aruI | gltB_1 | RS84_01565 | RS84_02996 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | Glutamate synthase [NADPH] large chain. | 0.556 |
aruI | ilvC | RS84_01565 | RS84_03232 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.986 |
aruI | ilvD_1 | RS84_01565 | RS84_01812 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.794 |
aruI | ilvD_2 | RS84_01565 | RS84_03235 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.872 |
aruI | ilvH | RS84_01565 | RS84_03233 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | Putative acetolactate synthase small subunit. | 0.996 |
aruI | leuB | RS84_01565 | RS84_03220 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.876 |
aruI | leuC | RS84_01565 | RS84_03184 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.657 |
aruI | leuD | RS84_01565 | RS84_03183 | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.663 |
gltB_1 | aruI | RS84_02996 | RS84_01565 | Glutamate synthase [NADPH] large chain. | Putative 2-ketoarginine decarboxylase AruI; Belongs to the TPP enzyme family. | 0.556 |
gltB_1 | ilvB1 | RS84_02996 | RS84_03234 | Glutamate synthase [NADPH] large chain. | Acetolactate synthase large subunit IlvB1. | 0.556 |
gltB_1 | ilvC | RS84_02996 | RS84_03232 | Glutamate synthase [NADPH] large chain. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.874 |
gltB_1 | ilvD_1 | RS84_02996 | RS84_01812 | Glutamate synthase [NADPH] large chain. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.871 |
gltB_1 | ilvD_2 | RS84_02996 | RS84_03235 | Glutamate synthase [NADPH] large chain. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.871 |
gltB_1 | ilvH | RS84_02996 | RS84_03233 | Glutamate synthase [NADPH] large chain. | Putative acetolactate synthase small subunit. | 0.823 |
gltB_1 | leuB | RS84_02996 | RS84_03220 | Glutamate synthase [NADPH] large chain. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.969 |
gltB_1 | leuC | RS84_02996 | RS84_03184 | Glutamate synthase [NADPH] large chain. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.809 |
gltB_1 | leuD | RS84_02996 | RS84_03183 | Glutamate synthase [NADPH] large chain. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.778 |
gltB_1 | xsc | RS84_02996 | RS84_02488 | Glutamate synthase [NADPH] large chain. | Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. | 0.556 |
ilvB1 | gltB_1 | RS84_03234 | RS84_02996 | Acetolactate synthase large subunit IlvB1. | Glutamate synthase [NADPH] large chain. | 0.556 |
ilvB1 | ilvC | RS84_03234 | RS84_03232 | Acetolactate synthase large subunit IlvB1. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |