STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD67661.1Uracil permease. (428 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.922
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.917
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.868
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.852
SDD54420.1
Carbamoyl-phosphate synthase small subunit.
  
  
 0.803
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.787
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  
 0.763
SDD78406.1
Phosphoribosylformylglycinamidine synthase.
  
  
 0.681
SDD32641.1
Dihydroorotate oxidase B, electron transfer subunit.
  
  
 0.663
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.628
Your Current Organism:
Peptococcus niger
NCBI taxonomy Id: 2741
Other names: ATCC 27731, DSM 20475, JCM 6506, Micrococcus niger, NCTC 11805, P. niger, VPI 7953
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