STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD98008.1Conserved hypothetical protein (putative transposase or invertase). (281 aa)    
Predicted Functional Partners:
SDD40720.1
DNA topoisomerase-3.
 
 
   0.513
SDD98052.1
Hypothetical protein.
       0.448
SDD98354.1
Serine phosphatase RsbU, regulator of sigma subunit.
  
    0.439
SDD98104.1
Single-strand binding protein.
       0.438
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.437
SDD97969.1
Conserved hypothetical protein (putative transposase or invertase).
 
    
0.428
Your Current Organism:
Peptococcus niger
NCBI taxonomy Id: 2741
Other names: ATCC 27731, DSM 20475, JCM 6506, Micrococcus niger, NCTC 11805, P. niger, VPI 7953
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