STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase (PFK); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.
 
 
 0.992
pgi
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
  
 0.973
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.963
fba
Fructose-bisphosphate aldolase (FBPA); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.961
fruK
Fructose-1-phosphate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
  
 0.940
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.937
tal
Transaldolase.
  
 
 0.932
gmuF
Phosphohexomutase; Function of strongly homologous gene; enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.919
gmuE
ROK fructokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.912
tpiA
Triose phosphate isomerase (TPI); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.824
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
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