STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SBO17735.1DNA polymerase, bacteriophage-type. (214 aa)    
Predicted Functional Partners:
fhs
Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
       0.616
yfmR
Uncharacterized ABC transporter ATP-binding protein YfmR.
       0.539
tsaB
tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.515
thyB
Thymidylate synthase B; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.455
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.445
dfrA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.426
SBO18220.1
Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.423
ctpA
Carboxy-terminal processing protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S41A family.
  
    0.421
aag
3-alkylated purines and hypoxanthine DNA glycosidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DNA glycosylase MPG family.
 
   
 0.419
ssbA
Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
   0.408
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
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