STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflBPyruvate formate lyase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (748 aa)    
Predicted Functional Partners:
pflA
Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.990
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.980
ADH
Aldehyde-alcohol dehydrogenase 2 (Includes: Alcohol dehydrogenase; Acetaldehyde dehydrogenase); In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.975
pyk
Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.
   
 
 0.942
eutE
Ethanolamine utilization protein eutE.
 
 
 0.938
pdhB
Pyruvate dehydrogenase (E1 beta subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.934
pta
Phosphate acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.933
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.932
yqeF
Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.927
pdhC
Pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.927
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
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