Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflAPyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (252 aa)    
Predicted Functional Partners:
pflB
Pyruvate formate lyase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.993
ADH
Aldehyde-alcohol dehydrogenase 2 (Includes: Alcohol dehydrogenase; Acetaldehyde dehydrogenase); In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.882
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.851
ppaC
Inorganic pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.573
acoB
Acetoin dehydrogenase E1 component beta-subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  
 0.533
pdhB
Pyruvate dehydrogenase (E1 beta subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  
 0.533
SBO17764.1
Transcription regulator; Belongs to the LysR transcriptional regulatory family.
       0.517
pdhC
Pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  
 0.516
pdhA
Pyruvate dehydrogenase (E1 alpha subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
  
 0.506
acoA
Acetoin dehydrogenase E1 component (TPP-dependent alpha subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  
 0.462
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
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