Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lytSTwo-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. (582 aa)    
Predicted Functional Partners:
lytT
Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator.
 0.997
SBO18120.1
Response regulator.
 
 
 0.900
lrgA-2
Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
   
 0.812
lrgB-2
Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
 
   
 0.695
SBO18403.1
Putative accessory gene regulator A, AgrA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
 
 0.588
ppaC
Inorganic pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.505
SBO16645.1
Putative accessory gene regulator, LytTR DNA-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 
 0.499
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.