| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SBO17770.1 | lrgA-2 | CDIV41_320333 | CDIV41_320331 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.454 |
| SBO17770.1 | lrgB-2 | CDIV41_320333 | CDIV41_320332 | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.454 |
| lrgA | lrgB-2 | CDIV41_320026 | CDIV41_320332 | LrgA family protein. | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.904 |
| lrgA-2 | SBO17770.1 | CDIV41_320331 | CDIV41_320333 | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | 0.454 |
| lrgA-2 | lrgB-2 | CDIV41_320331 | CDIV41_320332 | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.977 |
| lrgA-2 | lytS | CDIV41_320331 | CDIV41_320329 | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | Two-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. | 0.786 |
| lrgA-2 | lytT | CDIV41_320331 | CDIV41_320330 | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator. | 0.693 |
| lrgB-2 | SBO17770.1 | CDIV41_320332 | CDIV41_320333 | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function. | 0.454 |
| lrgB-2 | lrgA | CDIV41_320332 | CDIV41_320026 | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | LrgA family protein. | 0.904 |
| lrgB-2 | lrgA-2 | CDIV41_320332 | CDIV41_320331 | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.977 |
| lrgB-2 | lytS | CDIV41_320332 | CDIV41_320329 | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Two-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. | 0.646 |
| lrgB-2 | lytT | CDIV41_320332 | CDIV41_320330 | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator. | 0.785 |
| lytS | lrgA-2 | CDIV41_320329 | CDIV41_320331 | Two-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.786 |
| lytS | lrgB-2 | CDIV41_320329 | CDIV41_320332 | Two-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.646 |
| lytS | lytT | CDIV41_320329 | CDIV41_320330 | Two-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. | Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator. | 0.997 |
| lytT | lrgA-2 | CDIV41_320330 | CDIV41_320331 | Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator. | Antiholin factor; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.693 |
| lytT | lrgB-2 | CDIV41_320330 | CDIV41_320332 | Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator. | Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily. | 0.785 |
| lytT | lytS | CDIV41_320330 | CDIV41_320329 | Two-component response regulator (LytS); Function of homologous gene experimentally demonstrated in an other organism; regulator. | Two-component sensor histidine kinase (LytT); Function of homologous gene experimentally demonstrated in an other organism; receptor. | 0.997 |