STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (431 aa)    
Predicted Functional Partners:
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.996
SBO17131.1
NRPS-PKS protein putatively involved in antibiotic synthese; Function of strongly homologous gene; cell process.
 
 
 0.962
dltA
D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...]
  
 
 0.936
SBO17133.1
NRPS-PKS protein involved in antibiotic synthesis; Function of strongly homologous gene; cell process.
 
  
 0.910
gsaB
Glutamate-1-semialdehyde aminotransferase, class III aminotransferase; Function of strongly homologous gene; enzyme.
  
  
 
0.906
fabD
Malonyl CoA:acyl carrier protein transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.904
SBO17134.1
Function of strongly homologous gene; cell process.
  
 
 0.835
SBO17135.1
Function of strongly homologous gene; cell process.
 
 
 0.816
mazG
MazG nucleotide pyrophosphohydrolase domain protein.
       0.701
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.547
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
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