STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ykwCPutative beta-hydroxyacid dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (295 aa)    
Predicted Functional Partners:
fba
Fructose-bisphosphate aldolase (FBPA); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
    0.912
cpoA
Glycosyl transferases group 1 family protein.
       0.730
mprF
Conserved membrane hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.706
mazG
MazG nucleotide pyrophosphohydrolase domain protein.
      0.667
rfaG
Glycosyl transferases group 1 family protein.
       0.662
SBO16457.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.598
SBO17135.1
Function of strongly homologous gene; cell process.
  
  
 0.536
ADH
Aldehyde-alcohol dehydrogenase 2 (Includes: Alcohol dehydrogenase; Acetaldehyde dehydrogenase); In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.533
ptsH
Histidine-containing phosphocarrier protein of the phosphotransferase system (PTS) (HPr protein; Function of homologous gene experimentally demonstrated in an other organism; factor.
     
 0.447
ptsI
Enzyme I of the phosphotransferase system; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
       0.430
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
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