STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptsIEnzyme I of the phosphotransferase system; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (573 aa)    
Predicted Functional Partners:
ptsH
Histidine-containing phosphocarrier protein of the phosphotransferase system (PTS) (HPr protein; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
 0.999
ptbA
PTS system, glucose subfamily, IIA component domain protein.
 
 0.977
fruA
Phosphotransferase system (PTS) fructose-specific enzyme IIABC component; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.957
ptbA-2
PTS system, glucose subfamily, IIA component domain protein.
 
 0.936
bglF
Fused beta-glucoside-specific PTS enzymes: IIA component; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 
 0.927
SBO17213.1
PTS system, beta-glucoside-specific IIABC component.
 
 
 0.895
SBO17197.1
PTS system, beta-glucoside-specific IIABC subunit.
  
 
 0.836
bglP
PTS system beta-glucoside-specific EIIBCA component (Includes: Beta-glucoside-specific phosphotransferase enzyme IIB component; Beta-glucoside permease IIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component).
  
 
 0.836
scrA
PTS beta-glucoside transporter subunit EIIBCA; PTS system sucrose-specific EIIBCA component (Includes: Sucrose-specific phosphotransferase enzyme IIB component; Sucrose permease IIC component; Sucrose-specific phosphotransferase enzyme IIA component).
  
 
 0.836
hprK
Serine/threonine protein kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly [...]
 
   
 0.812
Your Current Organism:
Carnobacterium divergens
NCBI taxonomy Id: 2748
Other names: ATCC 35677, C. divergens, CCUG 30094, CIP 101029, Carnibacterium divergens, DSM 20623, IFO 15683, JCM 5816, JCM 9133, LMG 9199, LMG:9199, Lactobacillus divergens, NBRC 15683, NCDO 2763, NCIMB 11952, NCTC 13772, NRRL B-14830, strain 66
Server load: low (32%) [HD]