node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
divIVA | ftsA | CDIV41_40052 | CDIV41_40058 | Septum site-determining divIVA domain protein. | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.756 |
divIVA | ftsZ | CDIV41_40052 | CDIV41_40057 | Septum site-determining divIVA domain protein. | Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.777 |
divIVA | minC | CDIV41_40052 | CDIV41_320010 | Septum site-determining divIVA domain protein. | Septum formation inhibitor MinC, C-terminal domain protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.618 |
divIVA | murG | CDIV41_40052 | CDIV41_40060 | Septum site-determining divIVA domain protein. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.496 |
divIVA | sepF | CDIV41_40052 | CDIV41_40055 | Septum site-determining divIVA domain protein. | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.847 |
divIVA | ylmE | CDIV41_40052 | CDIV41_40056 | Septum site-determining divIVA domain protein. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.807 |
divIVA | ylmG | CDIV41_40052 | CDIV41_40054 | Septum site-determining divIVA domain protein. | Factor involved in shape determination and osmotic tolerance; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.799 |
divIVA | ylmH | CDIV41_40052 | CDIV41_40053 | Septum site-determining divIVA domain protein. | S4 domain protein. | 0.699 |
ftsA | divIVA | CDIV41_40058 | CDIV41_40052 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Septum site-determining divIVA domain protein. | 0.756 |
ftsA | ftsZ | CDIV41_40058 | CDIV41_40057 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.999 |
ftsA | mreB | CDIV41_40058 | CDIV41_320007 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell-shape determining protein; Function of homologous gene experimentally demonstrated in an other organism; cell process. | 0.470 |
ftsA | murG | CDIV41_40058 | CDIV41_40060 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.829 |
ftsA | secA | CDIV41_40058 | CDIV41_120033 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Translocase binding subunit (ATPase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.867 |
ftsA | sepF | CDIV41_40058 | CDIV41_40055 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.892 |
ftsA | ylmE | CDIV41_40058 | CDIV41_40056 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.776 |
ftsA | ylmG | CDIV41_40058 | CDIV41_40054 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Factor involved in shape determination and osmotic tolerance; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.777 |
ftsA | ylmH | CDIV41_40058 | CDIV41_40053 | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | S4 domain protein. | 0.710 |
ftsZ | divIVA | CDIV41_40057 | CDIV41_40052 | Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Septum site-determining divIVA domain protein. | 0.777 |
ftsZ | ftsA | CDIV41_40057 | CDIV41_40058 | Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Cell-division protein essential fo Z-ring assembly; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.999 |
ftsZ | minC | CDIV41_40057 | CDIV41_320010 | Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Septum formation inhibitor MinC, C-terminal domain protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.820 |