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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ODJ58741.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.815
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.569
gcvH
Glycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
    
 0.566
ODJ59885.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
     
 0.556
ODJ58740.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.546
ODJ58707.1
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.519
ODJ58097.1
NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  
  
 0.494
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.483
ODJ60106.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.472
ODJ60147.1
GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.472
Your Current Organism:
Brochothrix thermosphacta
NCBI taxonomy Id: 2756
Other names: ATCC 11509, B. thermosphacta, CCUG 35132, CIP 103251, DSM 20171, IFO 12167, JCM 20628, LMG 17208, LMG:17208, Microbacterium thermosphactum, NBRC 12167, NCIB 10018, NCIB:10018, NCTC 10822
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