STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGQ23063.2Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)    
Predicted Functional Partners:
KIX84814.1
Membrane protein/domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.840
KIX84815.1
Prevent-host-death protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.546
KGQ23073.1
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.546
KGQ21227.1
Ribonucleotide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.468
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.413
secF
Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
   
 0.409
rlpA
Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
   
 0.409
KIX84813.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.404
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.