| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KGQ21321.2 | KGQ22546.2 | THFILI_00930 | THFILI_08475 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| KGQ21321.2 | nfo | THFILI_00930 | THFILI_00870 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.588 |
| KGQ21321.2 | nth | THFILI_00930 | THFILI_05200 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.692 |
| KGQ21321.2 | polA | THFILI_00930 | THFILI_06865 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity. | 0.999 |
| KGQ21321.2 | rlpA | THFILI_00930 | THFILI_00875 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.490 |
| KGQ21321.2 | topA | THFILI_00930 | THFILI_04890 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
| KGQ21544.2 | ileS | THFILI_00880 | THFILI_00885 | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.586 |
| KGQ21544.2 | nfo | THFILI_00880 | THFILI_00870 | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.682 |
| KGQ21544.2 | rlpA | THFILI_00880 | THFILI_00875 | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.720 |
| KGQ22546.2 | KGQ21321.2 | THFILI_08475 | THFILI_00930 | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| KGQ22546.2 | nfo | THFILI_08475 | THFILI_00870 | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.431 |
| KGQ22546.2 | nth | THFILI_08475 | THFILI_05200 | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.571 |
| KGQ22546.2 | polA | THFILI_08475 | THFILI_06865 | DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity. | 0.988 |
| KGQ22910.1 | nfo | THFILI_06245 | THFILI_00870 | Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.474 |
| KIX84364.1 | nfo | THFILI_09630 | THFILI_00870 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.447 |
| ileS | KGQ21544.2 | THFILI_00885 | THFILI_00880 | isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
| ileS | nfo | THFILI_00885 | THFILI_00870 | isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.400 |
| ileS | polA | THFILI_00885 | THFILI_06865 | isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity. | 0.524 |
| ileS | topA | THFILI_00885 | THFILI_04890 | isoleucyl-tRNA synthase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.530 |
| nfo | KGQ21321.2 | THFILI_00870 | THFILI_00930 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |