| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KGQ21321.2 | hisI | THFILI_00930 | THFILI_10055 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.519 |
| KGQ21321.2 | mutM | THFILI_00930 | THFILI_09165 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.696 |
| KGQ21321.2 | nfo | THFILI_00930 | THFILI_00870 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.521 |
| KGQ21321.2 | nth | THFILI_00930 | THFILI_05200 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.573 |
| KGQ21321.2 | polA | THFILI_00930 | THFILI_06865 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity. | 0.998 |
| KGQ21321.2 | topA | THFILI_00930 | THFILI_04890 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.991 |
| KGQ21544.2 | nfo | THFILI_00880 | THFILI_00870 | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.690 |
| KGQ21544.2 | rlpA | THFILI_00880 | THFILI_00875 | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.723 |
| KGQ22910.1 | nfo | THFILI_06245 | THFILI_00870 | Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.443 |
| KIX84364.1 | nfo | THFILI_09630 | THFILI_00870 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.477 |
| KIX84364.1 | polA | THFILI_09630 | THFILI_06865 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity. | 0.439 |
| hisI | KGQ21321.2 | THFILI_10055 | THFILI_00930 | Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.519 |
| hisI | nfo | THFILI_10055 | THFILI_00870 | Imidazole glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.455 |
| mutM | KGQ21321.2 | THFILI_09165 | THFILI_00930 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
| mutM | nfo | THFILI_09165 | THFILI_00870 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.409 |
| mutM | polA | THFILI_09165 | THFILI_06865 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity. | 0.709 |
| nfo | KGQ21321.2 | THFILI_00870 | THFILI_00930 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.521 |
| nfo | KGQ21544.2 | THFILI_00870 | THFILI_00880 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.690 |
| nfo | KGQ22910.1 | THFILI_00870 | THFILI_06245 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
| nfo | KIX84364.1 | THFILI_00870 | THFILI_09630 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.477 |
