Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KIX84793.1Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family. (292 aa)    
Predicted Functional Partners:
KGQ21541.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.965
KGQ21058.2
Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.881
KGQ22437.1
Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.875
KGQ22035.2
CobQ/CobB/MinD/ParA domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.870
KIX84710.1
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.653
rsmG
16S rRNA methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.552
KIX84785.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.548
KGQ21514.1
N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.548
KIX84786.1
Plasmid replication initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.508
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.483
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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