Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGQ21847.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)    
Predicted Functional Partners:
KIX84776.1
Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA photolyase family.
  
  
 0.935
KGQ22956.2
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.541
thiI
Hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.532
KGQ21844.1
Arsenite oxidase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.508
KGQ21848.1
Arsenite oxidase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.492
cobB
NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
    
 0.491
KGQ21833.2
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.446
KGQ21226.1
RNA polymerase sigma E protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.415
pheT
phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.413
KGQ20925.1
Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.410
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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