Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGQ20977.22-hydroxypenta-2,4-dienoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)    
Predicted Functional Partners:
KGQ22148.2
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.947
KGQ20975.2
2,6-dioxo-6-phenylhexa-3-enoate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.938
KGQ22147.2
4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.924
KIX84730.1
4-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family.
 
  
 0.872
KGQ20978.1
4-oxalocrotonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.809
KGQ20971.1
Betaine-aldehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.797
KIX84729.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.746
KIX84724.1
Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.731
KGQ21599.2
Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.729
KIX84731.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.645
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.