KIX84739.1 protein (Thermus filiformis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Thermus filiformis

NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGQ21603.1	KGQ21696.1	THFILI_01535	THFILI_01500	precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.772
KGQ21603.1	KGQ22209.1	THFILI_01535	THFILI_01860	precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.541
KGQ21603.1	KIX84722.1	THFILI_01535	THFILI_01525	precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.999
KGQ21603.1	KIX84739.1	THFILI_01535	THFILI_01835	precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin--nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.826
KGQ21603.1	KIX84741.1	THFILI_01535	THFILI_01845	precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.825
KGQ21696.1	KGQ21603.1	THFILI_01500	THFILI_01535	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.772
KGQ21696.1	KGQ22206.2	THFILI_01500	THFILI_01865	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.561
KGQ21696.1	KGQ22209.1	THFILI_01500	THFILI_01860	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.811
KGQ21696.1	KIX84722.1	THFILI_01500	THFILI_01525	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.729
KGQ21696.1	KIX84739.1	THFILI_01500	THFILI_01835	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Ferredoxin--nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.910
KGQ21696.1	KIX84740.1	THFILI_01500	THFILI_01840	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.642
KGQ21696.1	KIX84741.1	THFILI_01500	THFILI_01845	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
KGQ21696.1	KIX84742.1	THFILI_01500	THFILI_01850	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.	0.855
KGQ22206.2	KGQ21696.1	THFILI_01865	THFILI_01500	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.561
KGQ22206.2	KGQ22209.1	THFILI_01865	THFILI_01860	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
KGQ22206.2	KIX84739.1	THFILI_01865	THFILI_01835	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin--nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.971
KGQ22206.2	KIX84740.1	THFILI_01865	THFILI_01840	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
KGQ22206.2	KIX84741.1	THFILI_01865	THFILI_01845	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
KGQ22206.2	KIX84742.1	THFILI_01865	THFILI_01850	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.	0.990
KGQ22206.2	KIX84743.1	THFILI_01865	THFILI_01855	Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.810