Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGQ22043.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.925
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.922
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
  0.886
KIX84708.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.850
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.843
KGQ22045.2
Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.814
sigA
RNA polymerase sigma70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.790
KGQ23022.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.777
KGQ21503.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
KGQ22413.2
CRISPR-associated protein Csm5; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.764
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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