Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGQ23100.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)    
Predicted Functional Partners:
KIX84751.1
Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.973
KGQ21879.2
anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
     0.745
KIX84750.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.717
KGQ21878.1
N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.679
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.647
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.589
KGQ21922.1
Beta lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.550
KGQ22479.1
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
KGQ22875.1
Peptigoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.463
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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