Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
KIX84768.1Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)    
Predicted Functional Partners:
KGQ21857.1
Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.850
KIX84670.1
CbbX; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.837
KGQ21489.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.825
KGQ22395.2
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
  0.806
cobB
NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
    
 0.804
KGQ22143.1
TonB box-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.783
KGQ22142.2
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.781
KGQ22136.1
ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TtcA family.
       0.777
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.777
KGQ21665.2
Pyrrolidone carboxyl peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
    
   0.758
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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