| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KGQ22579.1 | KIX84683.1 | THFILI_03335 | THFILI_03340 | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cation tolerance protein CutA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.464 |
| KGQ22579.1 | gyrA | THFILI_03335 | THFILI_03345 | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.610 |
| KGQ22579.1 | rpoC | THFILI_03335 | THFILI_06540 | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.691 |
| KIX84683.1 | KGQ22579.1 | THFILI_03340 | THFILI_03335 | Cation tolerance protein CutA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.464 |
| KIX84683.1 | gyrA | THFILI_03340 | THFILI_03345 | Cation tolerance protein CutA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.793 |
| dnaK | gyrA | THFILI_05300 | THFILI_03345 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.739 |
| dnaK | gyrB | THFILI_05300 | THFILI_05170 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.691 |
| dnaK | metG | THFILI_05300 | THFILI_04010 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.505 |
| dnaK | rpoC | THFILI_05300 | THFILI_06540 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.461 |
| dnaK | secF | THFILI_05300 | THFILI_00795 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.501 |
| dnaK | thrS | THFILI_05300 | THFILI_06225 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.647 |
| gyrA | KGQ22579.1 | THFILI_03345 | THFILI_03335 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| gyrA | KIX84683.1 | THFILI_03345 | THFILI_03340 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Cation tolerance protein CutA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
| gyrA | dnaK | THFILI_03345 | THFILI_05300 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.739 |
| gyrA | gyrB | THFILI_03345 | THFILI_05170 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| gyrA | metG | THFILI_03345 | THFILI_04010 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.808 |
| gyrA | nusA | THFILI_03345 | THFILI_00815 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.647 |
| gyrA | recA | THFILI_03345 | THFILI_06570 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.618 |
| gyrA | rpoC | THFILI_03345 | THFILI_06540 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.616 |
| gyrA | secF | THFILI_03345 | THFILI_00795 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.710 |