Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
KIX84687.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)    
Predicted Functional Partners:
ruvB
ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.804
KGQ22467.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.775
KGQ22103.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
KGQ23121.2
DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.766
KGQ22121.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.765
KGQ22892.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.763
KGQ22632.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.743
KIX84372.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.724
KGQ21052.2
Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.718
KGQ22278.1
Tfp pilus assembly protein PilF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.711
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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