KIX84689.1 protein (Thermus filiformis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Thermus filiformis

NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGQ20993.1	KGQ21784.1	THFILI_09965	THFILI_06355	Glyoxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.823
KGQ20993.1	KGQ22308.1	THFILI_09965	THFILI_03090	Glyoxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family.	0.800
KGQ20993.1	KIX84689.1	THFILI_09965	THFILI_03510	Glyoxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-aminoadipate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.803
KGQ21050.1	KGQ21634.1	THFILI_08665	THFILI_09185	Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
KGQ21050.1	KIX84689.1	THFILI_08665	THFILI_03510	Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-aminoadipate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.790
KGQ21634.1	KGQ21050.1	THFILI_09185	THFILI_08665	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
KGQ21634.1	KGQ21784.1	THFILI_09185	THFILI_06355	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.531
KGQ21634.1	KGQ23134.1	THFILI_09185	THFILI_10145	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
KGQ21634.1	KIX84689.1	THFILI_09185	THFILI_03510	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-aminoadipate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.854
KGQ21634.1	gcvH	THFILI_09185	THFILI_00675	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.909
KGQ21634.1	gcvPB	THFILI_09185	THFILI_00685	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.910
KGQ21634.1	gcvT	THFILI_09185	THFILI_00670	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.	0.902
KGQ21634.1	glyA	THFILI_09185	THFILI_05850	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.915
KGQ21784.1	KGQ20993.1	THFILI_06355	THFILI_09965	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glyoxylate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.823
KGQ21784.1	KGQ21634.1	THFILI_06355	THFILI_09185	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.531
KGQ21784.1	KGQ22308.1	THFILI_06355	THFILI_03090	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family.	0.820
KGQ21784.1	KIX84689.1	THFILI_06355	THFILI_03510	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-aminoadipate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.799
KGQ21784.1	gcvH	THFILI_06355	THFILI_00675	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.798
KGQ21784.1	gcvPB	THFILI_06355	THFILI_00685	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.798
KGQ21784.1	gcvT	THFILI_06355	THFILI_00670	Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.	0.815