Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGQ21386.1Sulfonate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (54 aa)    
Predicted Functional Partners:
KGQ21383.1
Lysine biosynthesis protein LysX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family.
 
   
 0.958
lysY
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
 
     0.912
lysZ
Acetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily.
 
   
 0.864
KGQ21385.2
Paraquat-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.807
leuD
Homoaconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
     0.801
leuC
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
     0.788
lysK
Acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
  
     0.741
KGQ22051.2
1,4-alpha-glucan branching protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 57 family.
       0.529
KGQ21390.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.523
KIX84593.1
Toxin HicA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.523
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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