Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KIX84599.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)    
Predicted Functional Partners:
KGQ22166.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.727
KGQ21836.2
Modification methylase HemK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.556
KGQ21883.2
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.537
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.537
KGQ22620.1
Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.516
KGQ22872.1
Adenine glycosylase; Adenine glycosylase active on G-A mispairs.
  
     0.516
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
     0.509
KGQ21882.2
Xanthorhodopsin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.413
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
     0.407
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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