Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
rtcBtRNA-splicing ligase RtcB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (877 aa)    
Predicted Functional Partners:
KGQ21927.2
Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.980
KGQ22660.2
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
   
 0.797
KIX84603.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.633
KIX84604.1
Periplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.605
KGQ21001.1
Peptide chain release factor 3; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.557
KGQ21137.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.510
KGQ20939.1
NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.447
KGQ21138.1
Septum formation initiator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.414
KGQ22136.1
ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TtcA family.
  
     0.409
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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