Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (475 aa)    
Predicted Functional Partners:
KGQ23053.1
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.844
KGQ21261.2
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.811
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.811
KGQ22262.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.809
KGQ21158.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.791
KGQ21383.1
Lysine biosynthesis protein LysX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family.
  
 
 0.651
KGQ21207.1
Succinyldiaminopimelate aminotransferase; Catalyzes the formation of N-succinyl-2-L-amino-6-oxoheptanedioate and L-glutamate from N-succinyl-L-2,6-diaminoheptanedioate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.590
KGQ22839.2
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.585
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.537
KGQ22112.2
Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.491
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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