Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KGQ21160.2Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)    
Predicted Functional Partners:
KGQ21162.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.818
KGQ21159.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.786
KGQ21161.1
Flavin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.686
KGQ21164.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.682
KGQ21173.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.569
KGQ21177.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
KGQ22123.2
Polya polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
   
 
 0.462
KIX84600.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.416
KGQ21965.1
Purine NTP phosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.410
KGQ21157.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.400
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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