Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGQ21157.2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)    
Predicted Functional Partners:
KGQ21634.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.887
KGQ22839.2
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.720
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.679
KGQ22918.1
Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.655
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.644
KGQ22313.1
Cytochrome C biogenesis protein CcsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.600
KGQ23038.1
Cytochrome C biogenesis protein CcsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.600
KGQ22909.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.600
KGQ22921.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.600
KGQ22321.2
Cytochrome C552; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.600
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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