Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIX84640.1NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)    
Predicted Functional Partners:
KGQ21260.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
KGQ21265.2
Pyridine nucleotide transhydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.998
cobB
NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
     
  0.788
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
  0.788
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
     
  0.788
KGQ21275.2
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
KGQ21279.2
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
KGQ21272.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.547
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.478
KIX84641.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.470
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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