STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recXRecombinase RecX; Modulates RecA activity; Belongs to the RecX family. (148 aa)    
Predicted Functional Partners:
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.956
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.852
KGQ23106.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.771
KGQ23122.1
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.680
KIX84503.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
     
 0.614
polA
DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity.
     
 0.590
KGQ23110.2
Stage V sporulation protein S; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.580
KGQ23123.1
CAAX protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.572
KGQ23124.2
AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.572
KGQ21321.2
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.545
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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