STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGQ21358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)    
Predicted Functional Partners:
KGQ21321.2
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.875
KGQ22611.1
Chromosome segregation protein ScpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.764
KIX84503.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.575
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  0.551
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
  0.512
KIX84768.1
Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.509
KIX84637.1
Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.509
gyrB
DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.508
polA
DNA polymerase I; Has 5'-3' exonuclease activity and no 3'-5' exonuclease activity.
  
 
 0.508
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.503
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.