Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGQ21611.2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)    
Predicted Functional Partners:
KGQ21610.2
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.647
KIX84767.1
Conserved repeat protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.646
KGQ21097.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.630
KGQ22043.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.617
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
  0.608
KGQ21228.2
anti-sigmaE protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.604
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.598
KGQ22413.2
CRISPR-associated protein Csm5; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.595
KGQ21503.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
KGQ22749.2
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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