Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGQ22181.2Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (758 aa)    
Predicted Functional Partners:
KGQ22973.2
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.916
KIX84454.1
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.867
KIX84455.1
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.741
KGQ20963.2
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.658
KGQ22839.2
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.619
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.610
KGQ22075.2
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
       0.560
KIX84708.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.527
KGQ21640.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.470
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.