Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIX84560.13,4-dihydroxyphenylacetate 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)    
Predicted Functional Partners:
KGQ21656.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.899
KGQ21657.2
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.808
KGQ21113.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.739
KGQ21598.2
Pyoverdin chromophore biosynthetic protein pvcC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.681
KGQ21655.1
Betaine-aldehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.644
KGQ22803.1
2-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.619
KGQ21948.1
Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.619
KGQ20978.1
4-oxalocrotonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.577
KGQ20977.2
2-hydroxypenta-2,4-dienoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.573
nuoI
(4Fe-4S)-binding protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
  0.571
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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