Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGQ22647.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (761 aa)    
Predicted Functional Partners:
KGQ22652.2
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.812
KGQ22476.2
DtxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.753
KIX84566.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.752
KGQ21096.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.634
KGQ22839.2
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.595
KGQ22648.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.480
KGQ22918.1
Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.478
KGQ21751.2
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.471
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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