Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIX84571.1Dihydropteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)    
Predicted Functional Partners:
KGQ21701.1
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
 0.961
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.948
KGQ21702.2
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.945
rsmH
16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
  
 0.909
mraZ
Cell division protein MraZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MraZ family.
 
  
 0.862
KGQ21316.2
Cell division protein FtsQ; Essential cell division protein.
  
 
 0.848
KIX84369.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.839
murE
UDP-N-acetylmuramyl peptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
 
  
 0.804
KGQ21683.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.801
KGQ21700.1
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MurCDEF family.
 
  
 0.773
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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