STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGQ20880.2Stage II sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)    
Predicted Functional Partners:
mraZ
Cell division protein MraZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MraZ family.
      
 0.522
bshC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BshC family.
       0.501
KGQ20882.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.496
KGQ22963.1
Pyruvyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.469
mqnD
1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
       0.461
KGQ21490.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.459
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
     
 0.442
sbcD
Hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
      
 0.441
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.436
KGQ22573.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.434
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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