Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGQ22945.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)    
Predicted Functional Partners:
KIX84345.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.814
KGQ21897.2
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.673
KIX84344.1
2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.601
KGQ21894.2
Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family.
    
  0.568
KGQ21896.1
2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.548
KGQ21895.1
Glycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.548
KIX84340.1
Radical SAM protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.481
KIX84341.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.481
KIX84342.1
Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.481
KIX84343.1
Glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.481
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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