Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
comB2-phosphosulfolactate phosphatase; Catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ComB family. (241 aa)    
Predicted Functional Partners:
KGQ22935.1
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.619
KIX84667.1
2-phosphosulfolactate phosphatase; Catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ComB family.
     
  0.593
KGQ21733.2
Phosphosulfolactate phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.575
KIX84346.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.448
KGQ22956.2
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.433
KGQ22952.1
enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.424
KGQ22951.1
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.420
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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