STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIHypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (386 aa)    
Predicted Functional Partners:
KGQ21582.2
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.962
KGQ21042.1
rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.668
KGQ23104.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
    0.614
mnmA
Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
 
 0.552
KGQ21847.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.545
KGQ22933.2
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.543
KGQ22766.1
Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.522
KIX84757.1
Adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.515
rny
Ribonuclease; Endoribonuclease that initiates mRNA decay.
 
   
 0.511
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.426
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.