Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGQ21629.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)    
Predicted Functional Partners:
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.777
KGQ21627.2
acyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.776
KGQ21888.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.557
KGQ21634.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.494
KGQ23081.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.434
KGQ21624.1
ATPase (AAA+ superfamily); Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.431
KIX84456.1
Nickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.406
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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