Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIX84371.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (716 aa)    
Predicted Functional Partners:
KIX84369.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.873
trmJ
RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
 
     0.802
KGQ22458.2
Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.783
KGQ21477.2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.777
KIX84571.1
Dihydropteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.773
KGQ22707.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.759
KGQ21701.1
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
  
   
 0.744
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.706
KGQ21549.2
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.695
KGQ22573.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.681
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
Server load: low (40%) [HD]