Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KIX84385.1Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)    
Predicted Functional Partners:
KIX84384.1
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.807
purD
Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family.
       0.691
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
    0.689
KGQ21859.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PlsY family.
       0.655
KGQ21599.2
Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.524
KIX84724.1
Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.524
KGQ21862.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.477
KGQ21863.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.461
KGQ22766.1
Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.401
Your Current Organism:
Thermus filiformis
NCBI taxonomy Id: 276
Other names: ATCC 43280, DSM 4687, JCM 11600, T. filiformis, strain Wai33 A1
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